ADMISSION &
EXAMINATION RULES
&
SYLLABUS
FOR
Diploma in Pharmacy
SYLLABI
DIPLOMA FIRST
YEAR
ADMISSION & EXAMINATION RULES
FOR
DIPLOMA IN PHARMACY
(Approved by the Standing Committee of the
Academic Council in March 1997 to be effective from the Academic Session
1997-98 and applicable to all D. Pharm students)
1. Programme : Diploma in
Pharmacy (D. Pharm.)
It shall be a full time regular course.
During an academic year, a candidate shall
be enrolled only for one programme of study and shall not appear in any
other examination of this or any other university.
2. Duration : Two years
3. Medium of Instruction and
Examination : English
4. Eligibility for Admission
: A candidate seeking admission to this course must have:
(a)passed 10+2 examination from Central
Board of Secondary Education or any other examination recognized by Jamia
Hamdard as equivalent thereto, with at least 50% marks in the aggregate of
Physics, Chemistry and Biology subjects, and must have passed in each of
these subjects.
(b)qualified the admission test / interview
conducted by Jamia Hamdard.
(c)Completed the age of 17 years on or
before the first day of October of the year of admission.
Some seats are provided for those
candidates who opt for an additional course in Unani Pharmacy. All such
candidates will have to take all the examinations in Modern Pharmacy in
addition to the additional papers in Unani Pharmacy (Urdu medium). On the
successful completion of the course, these candidates will be entitled to
the award of degree in Modern Pharmacy and a separate certificate for
Unani course. Proficiency in Urdu, comparable to Matric standard is
essential for such candidates.
5.Course
Structure:
The number of hours of teaching in theory
as well as practical in the various subjects of Diploma in Pharmacy Part-I
and Part-II are listed below. Each academic year will have at least 180
working days. There will be a total of 500 hours of practical training
spread over a period of not less than 3 months. The course contents are
given in the Syllabus.
S.No. |
Subject |
Paper |
Number of |
Hours per |
Years |
|
|
No |
Theory |
Practical |
Total |
1. |
Part-I
Pharmaceutics-I |
I |
75 |
100 |
175 |
2. |
Pharmaceutical
Chemistry-I |
II |
75 |
75 |
150 |
3. |
Pharmacognosy |
III |
75 |
75 |
150 |
4. |
Biochemistry &
Clinical Pathology |
IV |
50 |
75 |
125 |
5. |
Human Anatomy &
Physiology |
V |
75 |
50 |
125 |
6. |
Health Education
& Community Pharmacy |
IV |
50 |
- |
50 |
|
|
|
400 |
375 |
775 |
|
Unani Pharmacy |
DU-I |
25 |
- |
25 |
1. |
Part-II
Pharmaceutics-II |
VII |
75 |
100 |
175 |
2. |
Pharmaceutical
Chemistry-II (Organic Chemistry) |
VIII |
100 |
75 |
175 |
3. |
Pharmacology &
Toxicology |
IX |
75 |
50 |
125 |
4. |
Pharmaceutical
Jurisprudence |
X |
50 |
- |
50 |
5. |
Drug Store &
Business Management |
XI |
75 |
- |
75 |
6. |
Hospital &
Clinical Pharmacy |
XII |
75 |
50 |
125 |
|
|
|
450 |
275 |
725 |
|
Unani Pharmacy |
DU-II |
15 |
10 |
25 |
6. Scheme of Examination:
The distribution of marks for theory and
practical work in different papers during the course of study is detailed
below. The duration of annual examination in theory as well as practical
papers will be 3 hours.
YEAR / Paper |
Marks in
Theory |
Total |
Marks in
Practical |
Total |
Grand Total
|
|
Annual |
Sessional |
|
Annual |
Sessional |
|
|
Part-I |
|
|
|
|
|
|
|
Pharmaceutics-I |
80 |
20 |
100 |
80 |
20 |
100 |
200 |
Pharmaceutical
Chemistry-I |
80 |
20 |
100 |
80 |
20 |
100 |
200 |
Pharmacognosy |
80 |
20 |
100 |
80 |
20 |
100 |
200 |
Biochemistry &
Clinical Pathology |
80 |
20 |
100 |
80 |
20 |
100 |
200 |
Human Anatomy &
Physiology |
80 |
20 |
100 |
80 |
20 |
100 |
200 |
Total |
|
|
600 |
|
|
500 |
1100 |
Unani Pharmacy |
80 |
20 |
100 |
- |
- |
- |
100 |
Part-II |
|
|
|
|
|
|
|
Pharmaceutics-II |
80 |
20 |
100 |
80 |
20 |
100 |
200 |
Pharmaceutical
Chemistry-II (Organic Chemistry) |
80 |
20 |
100 |
80 |
20 |
100 |
200 |
Pharmacology &
Toxicology |
80 |
20 |
100 |
80 |
20 |
100 |
200 |
Pharmaceutical
Jurisprudence |
80 |
20 |
100 |
80 |
20 |
100 |
200 |
Drug Store &
Business Management |
80 |
20 |
100 |
- |
- |
- |
100 |
Hospital &
Clinical Pharmacy |
80 |
20 |
100 |
80 |
20 |
100 |
200 |
Total |
|
|
600 |
|
|
400 |
1000 |
Unani Pharmacy |
80 |
20 |
100 |
80 |
20 |
100 |
200 |
7. Internal Assessment:
A.For the purpose of awarding Sessional
marks in theory paper, performance of student shall be evaluated on the
basis of at least two written tests. These will be given by the respective
teachers . The sessional marks in practicals shall be allotted on the
following basis ,
a. Actual performance in the
sessional examination- 10 marks
b. Day to day assessment in the
practical class work - 10 marks
B.Each theory test will be of two hours
duration. These will be conducted as per a schedule notified by the Dean,
Faculty of Pharmacy. Practical sessional tests will be conducted in
regular classes by respective teachers.
C.The marks obtained shall be notified in time by the respective
teachers and answer books shown to the students, if they wish so. The
sessional test answer books shall be retained in the department till the
end of the academic term.
D.There shall be at least three tests for each course and the average of
best two tests shall be taken to award the sessional marks. There will be
no provision for special or additional internal assessment tests.
E.A regular record of the marks for sessional test conducted in an
academic year shall be maintained by the teacher concerned/Head of
Department for each student.
F.The final sessional marks shall be submitted by the teachers to the
Head of the Department who shall forward the same to the Registrar, within
ten days of the last sessional test held. These marks shall also be
displayed on the Notice Board of the Department/Faculty.
8.Attendance:
A.All students must attend every lecture
and practical class. However, to account for late joining or other such
contingencies, the attendance requirement for appearing in the examination
shall be a minimum of 75% of the classes actually held.
B.In order to maintain the attendance record of a particular course, a
roll call will be taken by the teacher in every scheduled lecture and
practical class. For the purpose of attendance, every scheduled practical
class will be counted as one attendance unit, irrespective of the number
of contact hours.
C.The teacher in charge will consolidate the attendance record for the
lectures and practicals for each term. Attendance on account of
participation in the prescribed functions of NCC, NSS, Inter-university
sports, educational tours/field work shall be credited to the aggregate,
provided the attendance record, duly countersigned by the officer in
charge, is sent to the Dean of Faculty within two weeks of the
function/activity etc.
D.The statements of attendance of students shall be displayed on the
Department Notice Board at the close of each term as given in the
University Calendar. A copy of the same shall be sent to the Head of
Department/Office of Dean of Faculty for record Notice displayed on Notice
Board shall be deemed to be a proper notification, and so individual
notice shall be sent to students.
E.If a student is found to be continuously absent from the classes
without information for a period of 30 days, the teacher in-charge shall
report it to the Head of Department/Dean for striking off the name of such
a student from rolls. Such a student may, however, apply for readmission
within 15 days from the date of issue of the notice of striking off the
name. The request may be considered by the Dean for readmission. Such a
student shall not be readmitted after the prescribed period. Their
admission shall be effected on payment of prescribed readmission fees.
F.A student with less than 75% attendance of the lectures and practicals
separately in each subject/course in an academic year shall be detained
from appearing in the Annual University examination. The Dean of Faculty
concerned may consider application for the condonation of attendance upto
5% on account of sickness, provided the application for condonation of
attendance, duly certified by a Registered Medical practitioner/Public
Hospital had been submitted within 5 days from the recovery from illness.
Condonation of attendance on account of any other extenuating
circumstances may also be considered, provided the request is duly
supported by documentary evidence.
G.A student detained on account of attendance will be readmitted to the
same class in the next academic year on payment of current fees except
Enrolment fee, Identity card fee and Security deposits.
9.Eligibility for admission to
examination:
A student seeking admission to the
examination to be held at the end of each academic year must have pursued
a regular course of study for one academic year and must have completed
the prescribed attendance requirements. Further, a student admitted to any
course must pass the first year examination within two academic years, and
must complete the full course of study within the prescribed span period
of four years.
10.Annual and Supplementary
examination:
A.The Annual and Supplementary examinations
shall be held as per schedule given in the Academic Calendar of Jamia
Hamdard. The Supplementary examinations may normally be held after 30 days
from the declaration of results of the Annual examinations.
B.A candidate who fails to appear at the Annual examination or having
appeared in the Annual examination fails to pass in any subject(s) as
prescribed for the examination, may be allowed to appear in the remaining
subjects at the Supplementary examination.
C.A candidate will be given a total number of three attempts, inclusive
of the first attempt, to clear the papers in which he/she fails to qualify
(irrespective of the number of such papers). In exceptionally hard cases,
a student may be considered for grant of one last mercy chance.
D.Application for mercy chance with proper justification and a written
undertaking given by the student will be examined by the Dean of the
Faculty, and specific recommendations will be forwarded to the Registrar
for getting approval of the competent authority. The undertaking would be
to the effect that in case he/she does not clear the backlog in this final
attempt, he/she not have any further claim to continue the studies and
that his/her name may be struck off the rolls.
E.The duration of annual examination in theory as well as practical
papers will be 3 hours. Unless specified otherwise.
F.Examiners shall examine students orally during the Practical
examinational and take cognizance of their performance when marking their
papers.
G.A student shall not be declared to have passed the examination unless
he/she secures at least 40% marks in each of the subjects separately in
the theory as well as practical examinations, including sessional marks.
Each theory paper or practical examination shall be construed as a
separate paper.
H.Ten days vacation shall be given as preparatory holidays before the
commencement of Annual examinations.
I.The candidates will retain the Internal Assessment of the previous
examination, wherever applicable.
11.Promotion to next class:
A.All candidates who have appeared for all
the subjects and passed the Diploma in Pharmacy Part-I examination are
eligible for promotion to the Diploma in Pharmacy Part-II class. However,
failure in more than two subjects shall debar the candidate from promotion
to Part-II
B.After having appeared in Diploma in Pharmacy Part-II examination, a
candidate shall be eligible to undergo a practical training as per the
guidelines and rules prescribed by the Pharmacy Council of India in this
regard.
C.The certificate of Diploma in Pharmacy shall only be awarded after the
completion of the Practical Training.
12.Classification
of successful candidates:
A.The
result of the successful candidates shall be classified at the end of the
second year examination on the basis of the aggregate of all subjects,
Theory and Practicals, secured by the candidate in the I and II year
examinations, as indicated below:
Ist Division
: 60% and above
2nd
Division : 50%-59.9%
Pass :
40%-49%
B.Candidates securing 75% or above marks in any subjects(s) and have
passed in all the subjects in a year in first attempt shall be declared to
have obtained Distinction in that subject(s).
13.Span Period:
A.Students admitted to Diploma in Pharmacy course must pass the first
year examination within two years from their first admission to the
course.
B.Students must pass all the examinations
required for the award of the Diploma within a maximum period of four
years.
PHARMACEUTICS 1
Theory (75 hours)
1.
Introduction of different dosage forms.
Their classification with example and their relative applications.
Familiarization with new drug delivery systems.
2. Introduction to Pharmacopoeias with
special reference to the Indian Pharmacopoeia.
3. Metrology-Systems of weights and
measures. Calculations including conversion from one to another system,
Percentage calculations and adjustment of products. Use of allegation
method in calculations. Isotonic solutions.
4. Packaging of
Pharmaceuticals-Desirable features of a container-types of containers.
Study of glass and plastics as materials for containers and rubber as a
material for closures their merits and demerits. Introduction to aerosol
packaging.
5. Size reduction - Objectives, and
factors affecting size reduction, methods of size reduction- Study of
hammer mill, ball mill, fluid energy mill and disintegrator.
6. Size separation - Size separation
by sifting, Official standards for powders, Sedimentation methods of size
separation, Construction and working of Cyclone separator.
7. Mixing and Homogenization - Liquid
mixing and powder mixing, Mixing of semisolids. Study of Silverson Mixer-
Homogenizer, Planetary Mixer; Agitated powder mixer, Triple Roller Mill,
Propeller Mixer, Colloid Mill and Hand Homogenizer, Double cone mixer.
8 . Clarification and Filtration-Theory
of filtration, Filter media, Filter aids and selection of filters. Study
of the following filteration equipments-Filter Press, Sintered Filters.
Filter Candles, Metafilter.
9. Extraction and Galenicals
(a) Study of percolation and maceration and their modifications,
continuous hot extraction. Applications in the preparation of tinctures
and extracts. (b) Introduction to Ayurvedic dosage forms.
10. Heat processes - Evaporation -
Definition - Factors affecting evaporation - Study of evaporating still
and Evaporating Pan.
11. Distillation - Simple distillation
and Fractional distillation, Steam distillation and vacuum distillation.
Study of vacuum still, preparation of Purified Water I.P. and water for
Injection I.P. Construction and working of the still used for the same.
12. Introduction to drying processes -
Study of Tray Dryers, Fluidized Bed Dryer, Vacuum Dryer and Freeze Dryer.
13. Sterilization - Concept of
sterilization and its differences from disinfection - Thermal resistance
of microorganisms, Detailed study of the following sterilization
processes.
i) Sterilization with moist
heat, ii) Dry heat sterilization,
iii) Sterilization by
radiation, iv) Sterilization filtration and v)
Gaseous sterilization.
Aseptic techniques - Application of
sterilization processes in hospitals particularly with reference to
surgical dressings and intravenous fluids. Precautions for safe and
effective handling of sterilization equipment.
14. Processing of Tablets - Definition;
Different types of compressed tablets and their properties. Processes
involved in the production of tablets; Tablets excipients; Defects in
tablets; Evaluation of Tablets; Physical standards including
Disintegration and Dissolution. Tablet coating-Sugar coating-,film
coating, enteric coating and microencapsulation (Tablet coating may begin
an elementary manner).
15. Processing of Capsules Hard and
soft gelatin capsules; different sizes of capsules; filling of capsules;
handling and storage of capsules. Special applications of capsules.
16.Study of
immunological products like sera, vaccines, toxoids & their preparations.
PRACTICAL
(100 hours)
Preparation (minimum number stated against
each) of the following categories illustrating
different techniques involved.
1. Automatic waters 3.
7 . Cosmetic preparation- 3
2. Solutions 4.
8. Capsules 2
3. Spirits
2 9.
Tablets 2
4. Tinctures 4
10. Preparations involving sterilization - 2
5 . Extracts
2 11. Ophthalmic preparations
- 2
6 . Creams 2
12. Preparations involving asceptic
techniques 2
Books
Recommended: (Latest editions)
1. Remington's Pharmaceutical
Sciences. 2. The Extra Pharmacopoeia-Martindale.
PHARMACEUTICAL
CHEMISTRY-1
Theory (75 hours)
General discussion on the following
inorganic compounds including important physical and chemical properties,
medicinal and pharmaceutical uses, storage conditions and chemical
incompatibility.
a. Acids, bases and buffers - Boric acid*,
Hydrochloric acid, strong ammonium hydroxide, Calcium hydroxide, Sodium
hydroxide and official buffers.
b. Antioxidants - Hypophosphorous acid,
dioxide, Sodium bisulphite, Sodium meta-bisulphite., Sodium thiosulphate,
Nitrogen and Sodium Nitrite.
c. Gastrointestinal agents
i) Acidifying agents - Dilute
hydrochloric acid
ii) Antacids - Sodium bicarbonate,
Aluminium hydroxide gel, Aluminium Phosphate, Calcium carbonate, Magnesium
carbonate, Magnesium trisilicate, Magnesium oxide, combinations of antacid
preparations.
iii) Protective and Adsorbents. Bismuth
subcarbonate and Kaolin.
iv) Saline cathartics - Sodium
Potassium tartrate and Magnesium sulfate.
Topical Agents-
i) Protectives -Talc, Zinc Oxide,
Calamine, Zinc stearate, Titanium dioxide, Silicone polymers.
ii) Antimicrobials and Astringents -
Hydrogen peroxide, Potassium permanganate, Chlorinated lime, Iodine,
Solutions of iodine, Povidone - iodine, Boric acid, Borax, Silver nitrate,
Mild silver protein, Mercury, Yellow mercuric oxide, Ammoniated mercury.
iii) Sulfur and its compounds - Sublimed
sulfurs, Precipitated sulfur, Selenium sulfide.
iv) Astringents:- Alum and Zinc Sulphate.
(E) Dental Products, Sodium fluoride,
stannous fluoride, Calcium carbonate, Sodium meta phosphate, Dicalcium
phosphate, Strontium chloride, Zinc chloride.
(F)Inhalants - Oxygen, Carbon dioxide,
Nitrous oxide.
(G)Respiratory stimulants - Ammonium
carbonate.
(H)Expectorants and Emetics - Ammonium
chloride*, Potassium iodide, Antimony Potassium tartrate.
(1)Antidotes - Sodium nitrite
2.Major Intra and Extracellular
electrolytes-
(A) Electrolytes used for replacement
therapy - Sodium chloride and its preparations, Potassium chloride and its
preparations.
(B) Physiological acid-base balance and
electrolytes used- Sodium acetate, Potassium acetate, Sodium bicarbonate
injection, Sodium citrate, Potassium citrate, Sodium lactate injection,
Ammonium chloride and its injection.
(C) Combination of oral electrolyte
powders and solutions.
3. Inorganic Official compounds of
Iron, Iodine, Calcium Ferrous Sulfate and Calcium gluconate.
4. Radio pharmaceuticals and Contrast
media - Radio activity Alpha, Beta and Gamma Radiations, Biological
effects of radiations, Measurement of radio activity G.M. Counter - Radio
isotopes - their uses, storage and precautions with special reference to
the official preparations.
Radio Opaque Contrast media - Barium
sulfate.
5. Quality control of Drugs and
Pharmaceuticals - Importance of quality control, significant errors,
methods used for quality control, sources of impurities in
Pharmaceuticals. Limit tests for arsenic, chloride, sulfate, iron and
heavy metals.
6.Identification tests
for cations and anions as per Indian Pharmacopoeia.
PRACTICAL
(75 hours)
1 . Identification tests for
inorganic compounds particularly drugs and pharmaceuticals.
2. Limit test for chloride, sulfate,
arsenic, iron and heavy metals.
3. Amy of inorganic Pharmaceuticals
involving each of the following methods of
compounds marked with (*) under theory.
a. Acid-Base titrations (at least 3)
b.Redox titrations (One
each of Permanganometry and iodimetry).
C. Precipitation titrations (at least
2)
d. Complexometric titrations (Calcium
and Magnesium).
Books Recommended.. (latest editions)
1 Indian Pharmacopoeia.
PHARMACOGNOSY
Theory (75 hours)
1.
Definition, history and scope of
Pharmacognosy including indigenous system of
medicine.
2. Various systems of classification of
drugs of natural origin.
3. Adulteration and drug evaluation,
significance of Pharmacopoeial standards.
4. Brief outline of occurrence,
distribution outline of isolation, identification tests,.
therapeutic effects and pharmaceutical
applications of alkaloids, terpenoids, glycosides, volatile oils, tannins
and resins.
5. Occurrence, distribution,
organoleptic evaluation, chemical constituents including tests wherever
applicable and therapeutic efficacy of following categories of drugs
(a)Laxatives: Aloe,
Rhubarb, Castor oil, lspaghula, Senna.
(b) Cardiotonics - Digitalis, Aduna.
(c) Carminatives & G.I. regulators -
Umbelliferous fruits. Coriander, Fennel, Ajowan, Cardamom, Ginger, Black
pepper, Asafoetida, Nutmeg, Cinnamon, Clove.
(d) Astringents - Catechu.
(e) Drugs acting on nervous system -
Hyoscyamus, Belladonna, Aconite, Ashwagandha, Ephedra, Opium, Cannabis,
Nux vomica.
(f) Antihypertensives - Rauwolfia
(g)Antitussives - Vasaka, Tolu
balsam, Tulsi.
(h)Antirheumatics - Guggul,
Colchicum.
(i)Antitumour-Vinca.
(j)Antileprotics - Chaulmoogra
oil.
(k)Antidiabetics -
Pterocarpus, Gymnema sylvestre.
(1)Diuretics - Gokhru,
Punarnava.
(m) Antidysenterics - Ipecacuanha.
(n) Antiseptics and disinfectants -
Benzoin, Myrrh, Neem, Curcuma.
o) Antimalarials - Cinchona.
(p) Oxytocics - Ergot
(q)Vitamins - Shark
liver Oil and Amla
(r) Enzymes - Papaya, Diastase, Yeast
(r)Perfumes and
flavoring agents - Peppermint oil, Lemon oil, orange oil, lemon grass oil,
Sandalwood.
(t) Pharmaceutical aids - Honey, Arachis
Oil, Starch, Kaolin. Pectin, Olive Lanolin, Beeswax, Acacia,
Tragacanth, Sodium alginate, Agar, Guar gurn, Gelatin.
(u) Miscellaneous - Liquorice, Garlic,
Picrorhiza, Dioscorea, Linseed, Shatavari, Shankhupushpi,
Pyrethrum, Tobacco.
6. Collection and preparation of crude
drugs for the market as exemplified by Ergot, Opium, Rauwolfia,
Digitalis, Senna.
7. Study of source, preparation and
identification of fibres used in sutures and surgical dressings -
cotton, silk, wool and regenerated fibres.
8. Gross anatomical studies of :- Senna,
Datura, Cinnamon, Cinchona, Fennel, Clove, Ginger, Nux vomica,
Ipecacuanha.
PRACTICAL (75 hours)
1. Identification of drugs by
morphological characters.
2. Physical and chemical tests for
evaluation of drugs wherever applicable.
3. Gross anatomical studies (t.s.) of
the following drugs Senna, Datura, Cinnamon
Cinchona, Coriander, Fennel, Clove,
Ginger, Nux vomica, lpecacuanha.
4. Identification of fibres and
surgical dressings.
5. Identification of fibres and
surgical dressings.
BIOCHEMISTRY AND CLINICAL PATHOLOGY
Theory (50 hours)
1. Introduction to biochemistry.
2. Brief chemistry and role of
proteins, polypeptides and amino acids, classification,
Qualitative tests, Biological
value, Deficiency diseases.
3. Brief chemistry and role of
Carbohydrates, Classification, qualitative tests. Diseases related to
carbohydrate metabolism.
4. Brief chemistry
and role of Lipids, Classification, qualitative tests. Diseases related to
lipids metabolism.
5.Brief chemistry and
role of Vitamins and Coenzymes.
6. Role of minerals and water in life
processes.
7. Enzymes: Brief concept of enzymatic
action, factors affecting it, therapeutic and
pharmaceutical importance.
8.Brief concept of normal and abnormal
metabolism of proteins, carbohydrates and lipids.
9.Introduction to
pathology of blood and urine.
(a)Lymphocytes and
Platelets, their role in health and disease.
(b) Erythorcytes - Abnormal cells and
their significance.
(c) Abnormal constituents of
urine and their significance in diseases.
PRACTICAL
(75 hours)
1. Detection and identification of
Proteins, Amino acids, Carbohydrates and Lipids.
2.Analysis of normal and
abnormal constituents of Blood and Urine (Glucose, Urea, Creatine,
Creatinine, Creatinine,
Cholesterol, Alkaline phosphatase, Acid phosphatase, Bilirubin,
SGPT, SGOT, Calcium, Diastase,
Lipase).
3 . Examination of sputum and faeces
(microscopic & staining).
4. Practice in injecting drugs by
intramuscular, subcutaneous and intravenous routes.
Withdrawal of blood
samples.
HUMAN ANATOMY AND PHYSIOLOGY
Theory (75 hours)
1.Scope of Anatomy and
Physiology.
Definition of various terms used in
Anatomy
2. Structure of cell, function of its
components with special reference to mitochondria and
3. Elementary tissues of the body, i.e.
epithelial tissue, muscular tissue, connective tissue and
nervous tissue.
4. Structure and function of skeleton.
Classification of joints and their function, Joint disorder.
5.
Composition of blood, functions of blood
elements. Blood group and coagulation of blood. Brief information
regarding disorders of blood.
6. Name and functions of lymph glands.
7. Structure and functions of various
parts of the heart. Arterial and venous system with special
reference to the names and positions of main arteries and veins. Blood
pressure and its recording. Brief information about
cardiovascular disorders.
8. Various parts of respiratory system
and their functions. Physiology of respiration.
9. Various parts of urinary systems and
their functions, structure and functions of kidney. Physiology of
Urine formation. Pathophysiology of renal diseases and oedema.
10. Structure of skeletal muscle.
Physiology of muscle contraction. Names, positions,
attachments and functions of various skeletal muscles. Physiology of
neuromuscular junction.
11. Various parts of central nervous
system, brain and its parts, functions and reflex action. Anatomy
and Physiology of autonomic nervous system.
12. Elementary knowledge of structure and
functions of the organs of taste, smell, ear, eye and skin. Physiology
of pain.
13.Digestive system;
names of the various parts of digestive system and their functions.
Structure and functions of liver, physiology of digestion and absorption.
14. Endocrine glands and hormones:
Location of the glands, their hormones and functions.
Pituitary, Thyroid, Adrenal and
Pancreas.
15. Reproductive System: Physiology and
anatomy of Reproductive system.
PRACTICAL
(50 Hours)
1.Study of human
skeleton.
2.Study with the help of
charts and Models of the following systems and organs:
(a)Digestive system
(b)Respiratory system
(c)Cardiovascular system
(d)Urinary system
(e)Reproductive system
(f)Nervous system
(g)Eye
(h)Ear
3.Microscopic
examination of epithelial tissue, cardiac muscle, smooth muscle, Skeletal
muscle, connective tissue and nervous tissue.
4.Examination of blood
films for TLC, DLC and malarial parasite.
5.Determination of
clotting time of blood, erythrocyte sedimentation rate, and hemoglobin
value.
6.Recording of body
temperature, pulse, heart rate, blood pressure and ECG.
HEALTH EDUCATION AND COMMUNITY PHARMACY
Theory (50 hours)
1. Concept of health -
Definition of physical health, mental health, social health, spiritual
health - determinants of health, indicators
of health, concept of disease, natural history of diseases, the disease
agents, concept of prevention of diseases.
2. Nutrition and Health
Classification of foods, requirements, diseases induced due to
deficiency of proteins, vitamins and
minerals - treatment and prevention.
3. Demography and family planning -
Demography cycle, fertility, family planning, contraceptive methods,
behavioral methods, natural family planning method, chemical method,
mechanical methods, hormonal contraceptives, population problem of India.
4. First aid - Emergency treatment in
shock, snake-bite, bums, poisoning, heart disease, fractures and
resuscitation methods. Elements of minor surgery and dressings.
5. Environment and health - Sources of
water supply, water pollution, purification of water, health and air,
noise, light - solid waste disposal and control - medical entomology,
arthropod borne diseases and their control, rodents, animals and diseases.
6. Fundamental principles of
microbiology - classification of microbes, isolation,
staining techniques of organisms of common
diseases.
7. Communicable diseases - Causative
agents, mode of transmission and prevention.
(a) Respiratory infections - Chicken
pox, measles, influenza, diphtheria, whooping cough and tuberculosis.
(b) Intestinal infections:
Poliomyelitis, Hepatitis, Cholera, Typhoid, Food poisoning, Hookworm
infection.
(c) Arthropod borne infections - Plague,
Malaria, Filariasis.
(d) Surface infections - Rabies,
Trachoma, Tetanus, Leprosy.
(e) Sexually transmitted diseases -
Syphilis, Gonorrhea, AIDS.
8. Non-communicable diseases -
Causative agents, prevention, care and controls Cancer, Diabetes,
Blindness, Cardiovascular diseases.
9. Epidemiology its scope, methods,
uses, dynamics of disease transmission. Immunity and immunisation:
Immunoligical products and their dose schedule. Principles of diseases
control and prevention, hospital acquired infection, prevention and
control. Disinfection, types of disinfection, disinfection procedures, for
faeces, urine, sputum, room, linen, dead-bodies, instruments.
DIPLOMA SECOND YEAR
PHARMACEUTICS-II
Theory(75 hours)
1. Dispensing Pharmacy:
i)Prescriptions - Reading and understanding
of prescriptions; Latin terms commonly used (Detailed study is not
necessary), Modern methods of prescribing, adoption of metric system.
Calculations involved in dispensing.
ii) Incompatibilities in Prescriptions
- Study of various types of incompatibilities- physical chemical and
therapeutic.
iii) Posology- Dose and dosage of drugs,
Factors influencing dose, Calculations of doses on the basis of age, sex
and surface area. Veterinary doses.
2. Dispensed Medications:
(Note: A detailed study of the following
dispensed medication is necessary. Methods of preparation with theoretical
and practical aspects, use of appropriate containers and closures. Special
labeling requirements and storage conditions should be high-lighted).
i) Powders - Types of
Powders-Advantages and disadvantages of powders, Granules, Cachets and
Tablet triturates. Preparation of different types of powders encountered
in prescriptions. Weighing methods, possible errors in weighing, minimum
weighable amounts and weighing of a material below the minimum weighable
amount, geometric dilution and proper usage and care of dispensing
balance.
ii) Liquid Oral Dosage Forms:
(a) Monophasic - Theoretical aspects
including commonly used vehicles, essential adjuvant like stabilizers,
colorants and flavors, with examples.
Review of the following monophasic liquids
with details of formulation and practical methods.
Liquids for internal
administration Liquids for external administration or used on
mucous membranes
Mixtures and
concentrates Gargles
Syrups and Elixirs
Mouth washes, Throat-paints, Douches
Ear Drops, Nasal drops & Sprays
Liniments Lotions
(b) Biphasic Liquid Dosage Forms
i) Suspensions (elementary
study)-Suspensions containing diffusible solids and liquids and their
preparations. Study of the adjutants used like thickening agents, wetting
agents, their necessity and quantity to be incorporated. Suspension of
precipitate forming liquids like tinctures, their preparations and
stability. Suspensions produced by chemical reaction. An introduction to
flocculated/non- flocculated suspension system.
ii) Emulsions - Types of emulsions,
identification of emulsion systems, formulation of emulsions, selection of
emulsifying agents, Instabilities in emulsions, Preservation of
emulsions.
iii) Semi-Solid Dosage Forms:
(a) Ointments - Types of
ointments, classification and selection of dermatological
vehicles., Preparation and stability of ointments by the following
processes: (i) Trituration (ii)Fusion
(iii) Chemical reaction (iv) Emulsification.
(b) Pastes - An introduction to the
different types of jellies and their preparation.
(c) Jellies - An introduction to the
different types of jellies and their preparation.
(d) An elementary study of poultice.
(e) Suppositories and pessaries - Their
relatives merits and demerits, types of suppositories, suppository bases,
classification, properties, Preparation and packing of suppositories. Use
of suppositories for drug absorption.
iv) Dental and Cosmetic Preparations
Introduction to Dentrifices, Facial
cosmetics, Deodorants, Antiperspirants, Shampoos, Hair dressings and Hair
removers.
v) Sterile Dosage Forms
(a) Parenteral dosage forms -
Definition, General requirements for parenteral dosage forms. Types of
parenteral formulations, vehicles, adjuvants, processing, personnel,
facilities and Quality control. Preparation of Intravenous fluids and
admixtures-Total parenteral nutrition, Dialysis fluids.
(b) Sterility testing, Particulate
matter monitoring- Faulty seals-packaging.
(c) Ophthalmic Products - Study of
essential characteristics of different ophthalmic preparations.
Formulation additives, special precautions in handling and storage of
ophthalmic products.
PRACTICAL (100 hours)
Dispensing of at least 100 products
covering a wide range of preparations such as mixtures, emulsions,
lotions, liniment,N.,T-.. preparations, ointments, suppositories, powders,
incompatible prescriptions etc.
Books recommended (Latest
editions)
1.Indian Pharmacopoeia.
2.British Pharmacopoeia.
3.National Formularies (N.F.l.,
B.N.F.)
4.Remington's Pharmaceutical
Sciences.
5 . Martindale's Extra Pharmacopoeia.
PHARMACEUTICAL CHEMISTRY 11
Theory (100 hours)
1. Introduction to
the nomenclature of organic chemical systems with particular reference to
hetero-eyclic system containing upto 3 rings.
2. The Chemistry of following
Pharmaceutical organic compounds, covering their nomenclature, chemical
structure, uses and the important Physical and Chemical properties
(Chemical structure of only those compounds marked with asterisk(*).
The stability and storage conditions and
the different type of Pharmaceutical formulations of these drugs and their
popular brand names.
Antiseptics and Disinfectants - Proflavine*,
Benzalkonium chloride, Cetrimide, Chloro
cresol*, Chloroxylene, Formaldehyde
solution, Hexachlorophene, Liquified phenol, Nitro Furantoin.
Suifonamides - Sulfadiazine,
Sulfaguanidine*, Phthalyl sulfathiazole, Succinyl sulphathiazole
Sulfamethoxy pyridazine, Sulphadimethoxine, Sulfa methoxazole, co-
trimoxazole, Sulfacetamide*.
Antileprotic Drugs - Clofazimine,
Thiambutosine, Dapsone*, Solapsone.
Anti-tubercular Drugs - Isoniazid*, PAS*,
Streptomycin, Rifampicin, Ethambutol*, Thiacetazone, Ethionamide,
Cycloserine, Pyrazinamide*.
Antiamoebic and Anthelmintic Drugs -
Emetine,Metronidazole*, Halogenated hydroxyquinolines, diloxanide furoate,
Paromomycin Piperazine*, Mebendazole, D. E. C.
Antibiotics- Benzyl Penicillin*, Phenoxy
methyl Penicillin*, Benzathine Penicillin, Ampicillin*,
Cloxacillin, Carbenicillin, Cephaloridine, Cephalothin, Griseofulvin,
Chloramphenicol.
Antifungal agents - Undecylenic acid,
Tolnaftate, Nystatin, Amphotericin, Hamycin.
Antimalarial Drugs - Chloroquine*,
Amodiaquine, Primaquine, Proguanil, Pyrimethamine*, Quinine, Trimethoprim.
Tranquilizers - Chlorpromazine*, Prochlor
Perazine. Trifluperazine, Thiothixene, Haloperidol*, Triperidol,
Oxypertine, Chlordizepoxide, Diazepam, Loranpam, Meprobamate.
Hypnotics-Phenebarbitone*, Butobarbitone,
Cyclobarbitone, Ni Glutethimide* .'Methyprylon, paraldehyde, Triclofos-sodium.
General Anaesthtics - Halothane*,
Cyclopropane*, Diethyl ether*, Methohexital sodium, Thiopental sodium,
Trichloro ethylene.
Antidepressant Drugs - Amitriptyline,
Nortriptyline, Imipramine*, Tranyl cypromine.
Analeptics - Theophylline, Caffeine*,
Coramine*, Dextro-amphetamine.
Adrenergic Drugs - Adrenaline*,
Noradrenaline, Isoprenaline*, Phenylephrine, Salbutamol, Terbutaline,
Ephedrine*, Ephedrine*, Pseudo-ephedrine.
Adrenergic Antagonist - Tolazoline,
Propranolol*, Practalol.
Cholinergic Drugs- Neostigmine*,
Pyridostigmint, Pralidoxime, Pilocarpine, Physiostigmine*.
Cholinergic Antagonists - Atropine*,
Hyoscine, Homatropine, Propantheline, Benztropine, Tropicamide, Biperiden*.
Diuretic Drugs - Furosemide*,
Chlorothiazide, Hydrochlorothiazide*, Benzthiazide, Urea*, Mannitol*,
Etbacrynic Acid.
Cardiovascular Drugs - Ethyl nitrite*,
Glyceryl trinitrate, Alpha methyl dopa, Guanethidine, Clofibrate,
Quinidine.
Hypoglycemie Agents - Insulin,
Chlorpropamide*, Tolbutamide Glibenclamide, Phenformin*, Metformin.
Coagulants and Anti- Coagulant -
Heparin, Thrombin, Menadione's, Bishydroxycoumarin, Warfarin
sodium.
Local Anaesthetics - Lignocaine*, Procane*,
Benzocaine.
Histamine and Anti histaminic Agents -
Histamine, Diphenhydramine*, Promethazine, Cyproheptadine, Mepyramine,
Pheniramine, Chlorpheniramine*.
Analgesics and Anti-pyreties - Morphine,
Pethidine*, Codeine, Methadone, Aspirin*. Paracetamol*, Analgin,
Dextropropoxyphene, Pentazocine.
Non-steriodal anti-inflammatory Agents-
Indomethacin*, phenylbutazone*, Oxyphenbutazone, lbuprofen.
Thyroxine and Antithyroids- Thyroxine*,
Methimazole, Methyl thiouracil, Propylthiouracil.
Diagnostic Agents - lopanoic Acid,
Propyliodone, Sulfo-bromophtalein, Sodium, Indigotindisulfonate Sodium
(Indigo Carmine), Evans blue, Congo Red, Fluorescien Sodium.
*Anticonvulsants, cardiac glycosides,
Antiarrhythmic antihypertensives & vitamins.
Steroidal Drugs - Betamethazone, Cortisone,
Hydrocortisone, prednisolone, Progesterone, Testosterone, Oestradiol,
Nandrolone.
Anti-Neoplastic Drugs - Actinomycins,
Azathioprine, Busulphan, Chlorambucil, Cisplatin cyclophosphamide,
Daunorubicin, Hydrochloride, Fluorouracil, Mercaptopurine, Methotrexate,
Mitomycin.
PRACTICAL
1. Systematic qualitative
testing of organic drugs involving Solubility determination, melting point
and/or boiling point, detection of elements and functional groups (10
compounds).
2. Official identification tests for
certain groups of drugs included in the I.P. like barbiturates,
sulfonamides, phenothiazines, Antibiotics etc. (8 compounds).
2.Preparation of three
simple organic preparations.
Books Recommended: (Latest editions)
1 . Pharmacopoeia of India.
2. British Pharmaceutical Codex.
3. Martindale's Extra Pharmacopoeia.
PHARMACOLOGY AND TOXICOLOGY
Theory (75 hours)
1.Introduction to
Pharmacology
2.Routes of
administration of drugs, their advantages and disadvantages
3.Various processes of
absorption of drugs and the factors affecting them. Metabolism ,
Distribution and Excretion of drugs.
4.General mechanism of
drug action and the factors which modify drug action.
5.Pharmacological
classification of drugs. The discussion of drugs should emphasize the
following aspects:
I.Drug acting on central
nervous system
(a)General Anesthetics,
adjunction aneasthesia, Intravenous anaesthesia.
(b)Analgesic antipyretic
and non steroidal anti-inflammatory drugs, Narcotic analgesic, Anti
rheumatic and antigout remedies. Sedative and Hypnotics.
Psycopharmacological agents, Anticonvulsant and analeptics.
(c)Centrally acting
muscle relaxants and Antiparkinsonism agents
II.Local Anaesthetics
III.Drugs acting on
autonomic nervous system.
(a)Cholinergic drugs,
Anticholinergic drugs, Anticholinestrase drugs.
(b)Adrenergic drugs,
Adrenergic receptor blockers.
(c)Neurone blockers and
ganglion blockers.
(d)Neuromuscular blocker,
drug used in Mysthenia gravis.
IV Drugs acting on
eyes, Mydriatics, drugs used in glaucoma.
V
Drugs acting on respiratory system-Respiratory stimulant, Bronchodilators,
Nasal decongestant, expectorant and antitussive agents.
VI
Antacids, Physiological role of histamine and serotonin, Histamine and
anti histamine, Prostaglandins.
VII
Cardiovascular drugs, cardiotonic drugs, Antiarrythmic agents, Anti
anginal agents, Antihypertensive agents, Peripheral vasodilators, and
Drugs used in atherosclerosis.
VIII
Drugs acting on blood and blood forming organs, Heamatinics, Coagulants
and Anticoagulants, Heamostatics, Blood substitute and plasma expanders.
IX
Drugs affecting renal function- Diuretics and anti diuretics
X
Hormones and hormone antagonist- Hypoglycemic agents, Antithyroid drugs,
sex hormones and oral contraceptives, Corticosteroids.
XI
Drugs acting on Digestive system- Carminative, Digestant bitters, Antacids
and drugs used in peptic ulcers, Purgative and Laxative, Antidiarrhoeal,
emetics, Antiemetics, Antispasmodic.
6.Chemotherapy of
microbial diseases- Urinary antiseptics, Sulfonamides, Penicillins,
Streptomycin, Tetracyclines and other antibiotics.
7.Chemotherapy of
protozoal diseases- Anthelmintic drugs
8.Chemotherapy of cancer
9.Disinfectants and
antiseptics.
A detailed study of the action of drugs on
each organ is not necessary.
PHARMACOLOGY PRACTICAL
(50 hours)
The first six of the following experiments
will be done by the student while the remaining will be demonstrated by
the teacher.
1.Effects of K+
, Ca ++, acetyl choline and adrenaline on Frogs heart.
2.Effect of acetyl
choline on rectus abdominus muscle of Frog and Guinea pig ilium.
3.Effect of spasmogens
and relaxant on rabbits intestine.
4.Effect of local
anaesthetics on rabbit cornea.
5.Effect of Mydriatics
and myotics on Rabbits eye,
6.To study the action of
strychnine on frog .
7.Effects of digitalis
on frog's heart.
8.Effect of hypnotics in
mice.
9.Effect of convulsant
and anticonvulsant in mice and rats.
10.Test of pyrogens.
11.Taming and hypnosis
potentiating effect of chlorpromazine in mice/rats.
12.Effect of
diphenhydramine in experimentally produced asthma in guinea pigs.
PHARMACEUTICAL JURISPRUDENCE
Theory (50 hours)
1. Origin and nature of Pharmaceutical
legislation in India, its scope and objectives. Evolution of the 'Concept
of Pharmacy' as an integral part of the Health care system.
2. Principles and significance of
Professional Ethics. Critical study of the code of Pharmaceutical Ethics
drafted by Pharmacy Council of India.
3. Pharmacy Act, 1948 - The General study
of the Pharmacy Act with special reference to Education Regulations,
working of State and Central Councils, constitution of these councils and
functions. Registration procedures under the Act.
4. The Drugs and Cosmetics Act, 1940 -
General study of the Drugs and Cosmetics Act and the Rules thereunder.
Definitions and salient features related to retail and whole sale
distribution of drugs. The powers of Inspectors, the sampling procedures
and the procedure and formalities in obtaining licenses under the rule.
Facilities to be provided for running a Pharmacy effectively. General
study of the schedules with special reference to schedules C,C,F,G,JH,P
and X and salient features of labeling and storage conditions of drugs.
5.
The Drugs and Magic Remedies (Objectionable
Advertisement) Act, 1954 - General study of Act, Objectives, special
reference to he laid on Advertisements, Magic remedies and objectionable
and permitted advertisements-diseases which cannot be claimed to be cure.
6. Narcotic Drugs and Psychotropic
Substances Act, 1985-A brief study of the act with special reference to
its objectives, offences and punishment.
7. Brief introduction to the study of
the following acts:
1 . Latest Drugs (Price Control) Order
in force.
2. Poisons Act 1919 (as amended to
date)
3.Medicinal and Toilet
Preparations (Excise Duties) Act, 1955 (as amended to date)
4. Medical Termination of Pregnancy
Act, 1971 (as amended to date)
Books Recommended: (Latest edition)..
Bare Acts of the said laws published by the
Government.
DRUG STORE AND BUSINESS MANAGEMENT
Theory (75 hours)
Part 1 Commerce (50 hours)
1.
Introduction - Trade, Industry and
Commerce, Functions and subdivision of Commerce,
Introduction to Elements of
Economics and Management.
2.Forms of Business
Organizations.
3. Channels of Distribution.
4. Drug House Management - Selection of
Site, Space lay-out and legal requirements. Importance and objectives of
Purchasing, selection of suppliers, credit information, tenders, contracts
and price determination and legal requirements thereto. Codification,
handling of drug stores and other hospital supplies.
5. Inventory Control - objects and
importance, modern techniques like ABC, VED analysis,
the lead time, inventory carrying cost,
safety stock, minimum and maximum stock levels, economic order quantity,
scrap and surplus disposal.
6. Sales Promotion, Market Research,
Salesmanship, qualities of a salesman, Advertising and Window
Display.
7. Recruitment, training, evaluation
and compensation of the pharmacist.
8. Banking and Finance - Service and
functions of bank, Finance Planning and sources of finance.
Part 11 Accountancy (25 hours):
1. Introduction to the accounting
concepts and conventions, Double entry, Book keeping, Different kinds of
accounts.
2. Cash Book.
3. General Ledger and Trial Balance.
4. Profit and Loss Account and Balance
Sheet.
5. Simple techniques of analysing
financial statements.
Introduction to Budgeting
Books Recommended: (Latest editions)
1.Remington
Pharmaceutical Sciences.
HOSPITAL CLINICAL PHARMACY
Theory (75 hours)
Part-1: Hospital Pharmacy:
1.Hospitals- Definition
, Function , classification based on various criteria, organisation ,
management and health delivery system in India.
2.Hospital Pharmacy:
a)Definition
b)Function and
objectives of hospital pharmaceutical services.
c)Location , layout,
flow chart of materials and men.
d)Personnel and
facilities requirements including equipments based on individual and basic
needs.
e)Requirements and
abilities required for hospital pharmacist
3.Drug distribution
system in hospitals
a)Out-patient services
b)In-patient
services-(a) Types of services. (b) Detailed discussion of unit dose
system, floor ward stock system, satellite pharmacy services, central
sterile services, bed side pharmacy.
4.Manufacturing :
a)Economical
considerations, estimation of demand.
b)Sterile manufacture-
Large and small volume parenterals, facilities , requirements, layout,
production planning, men power requirements.
c)Non-sterile
manufacture- Liquid orals, externals, bulk concentrate.
d)Procurement of stores
and testing of raw materials.
5. Nomenclature and uses of surgical
instruments and hospital equipments and health accessories.
6. P.T.C. (Pharmacy Therapeutic
Committee), Hospital Formulary System and their organization, functioning,
composition.
7. Drug Information Service and Drug
Information Bulletin.
8. Surgical dressing like cotton, gauze,
bandages and adhesive tapes including their Pharmacopoeial tests for
quality. Other hospital supply e.g. I.V. sets, B.G. sets, Royal
tubes, Catheters, Syringes etc.
9. Application of computers in
maintenance of records, inventory control, medication monitoring, drug
information and data storage and retrieval in hospital and retail pharmacy
establishments.
Part II: Clinical Pharmacy
1. Introduction to Clinical Pharmacy
Practice - Definition, scope.
2. Modern dispensing aspects -
Pharmacists and Patient counseling and advice for the use
of common drugs, medication history.
3. Common daily terminology used in the
Practice of Medicine.
4. Disease, manifestations and
pathophysiology including salient symptoms to understand
the disease like Tuberculosis, Hepatitis,
Rheumatoid Arthritis, Cardio-vascular diseases, Epilepsy, Diabetes, Peptic
Ulcer, Hypertension.
5. Physiological parameters with their
significance. 6. Drug Interactions
(a) Definition and introduction.
(b) Mechanism of Drug interactions
(c) Drug - drug interaction with
reference to analgesics, diuretics, cardiovascular
drugs, Gastro-intestinal agents. Vitamins
and Hypoglycemic agents.
(d) Drug-food interaction.
7. Adverse Drug Reactions:
(a) Definition and significance
(b) Drug - induced diseases and
Teratogenicity.
8. Drugs in clinical toxicity-
Introduction , general treatment of poisoning, systematic poisoning, heavy
metal poison, Narcotic drugs, barbiturates, organophosphorous poisons.
9.Drug dependents, Drug
abuse, Addictive drugs and their treatment, complications.
10. Bio-availability of drugs, including
factors affecting it.
PRACTICAL (50 hours)
1 . Preparation of transfusion fluids.
2. Testing of raw materials used in (1)
3.Evaluation of surgical
dressings.
4.Sterilization of surgical
instruments, glass ware and other hospital supplies.
5.Handling and use of data
processing equipments.
Books Recommended. (Latest editions)
1Remington's
Pharmaceutical Sciences.
2. Martindale's
Extra pharmacopoeia.
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