The Department of Chemistry is a hub of innovative research that spans diverse and interdisciplinary domains, addressing key challenges at the interface of chemistry, biology, and material sciences. Our faculty and students actively contribute to cutting-edge research in the following areas:
1. Medicinal Chemistry
Research in this area focuses on discovering and designing bioactive molecules with therapeutic potential. Efforts are directed toward the synthesis and optimization of small molecules targeting diseases such as cancer, diabetes, and infectious conditions.
Key Highlights:
Structure-activity relationship (SAR) studies for drug discovery.
Development of novel inhibitors for molecular targets.
Collaboration with pharmaceutical companies for translational research.
2. Natural Products Chemistry
This research explores bioactive compounds derived from natural sources such as plants, fungi, and marine organisms. These compounds are studied for their potential as pharmacological agents and templates for synthetic modifications.
Focus Areas:
Isolation and structural characterization of natural products.
Development of natural product-inspired pharmacophores.
Sustainable extraction methods for bioactive molecules.
3. Anti-Cancer and Anti-Inflammatory Agents
The Department is involved in the design and synthesis of molecules targeting specific pathways associated with cancer progression and inflammation. This includes both small molecules and nanoparticle-based therapeutic platforms.
Research Goals:
Identifying novel drug candidates for oncology and inflammatory disorders.
Exploring nanotechnology for targeted drug delivery.
In vitro and in vivo evaluation of therapeutic efficacy.
4. Anti-Hyperglycaemic and Anti-Microbial Agents
Researchers are working on creating compounds that can regulate blood glucose levels and combat microbial infections. The development of these agents focuses on mechanisms that improve efficacy and minimize resistance.
Applications:
Targeting metabolic pathways for diabetes management.
Designing broad-spectrum anti-microbial agents, including anti-tubercular and anti-leishmanial compounds.
5. Nano-Synthesis and Drug Delivery
Nanotechnology is leveraged to create advanced materials for drug delivery systems, enhancing the precision and efficiency of therapeutic agents.
Innovations Include:
Development of nanostructures for controlled and targeted drug release.
Study of nano-bio interfaces for biocompatibility and effectiveness.
Use of molecular machines in drug delivery systems.
6. Soft Matter and Chemistry at the Nano-Bio Interface
This research area examines the interaction between soft materials, such as polymers and liquid crystals, and biological systems. The work focuses on understanding and designing systems that mimic or interact with biological structures.
Research Objectives:
Studying the behavior of soft materials in biological environments.
Developing biosensors and responsive materials.
Exploring the role of molecular machines in biophysical processes.
7. Molecular Machines
The Department investigates the application of molecular machines in various chemical and biological processes, including drug delivery and catalysis.
Areas of Study:
Design and synthesis of molecular machines for targeted applications.
Integration of molecular machines in nanotechnology.
Understanding dynamic properties and real-time applications.
The Department fosters collaboration with leading research institutions and industries globally to ensure that its research aligns with real-world challenges. Supported by funding from prestigious organizations like the Ministry of AYUSH, ICMR, DBT, DRDO, and UGC, the Department aims to translate its discoveries into impactful solutions for healthcare, environment, and industry.
By addressing critical problems through interdisciplinary research, the Department continues to contribute to the advancement of chemical sciences and the betterment of society.
